BCMB Rocks!

Wow  — we all know our BCMB graduates are outstanding scientists, but check this out:

In the current issue of Science, two BCMB grads are first authors of RESEARCH ARTICLES!  Clara Bien Peek worked with Peter Espenshade and is currently a postdoc with Joseph Bass at Northwestern.  Jason McLellan worked with Dan Leahy, and recently started as an Assistant Professor at Dartmouth after a postdoc at the NIH with Peter Kwong.

Here are the links to these papers:

http://www.sciencemag.org/content/342/6158/1243417.full

http://www.sciencemag.org/content/342/6158/592.full

Congrats Clara and Jason!
claraJason

Publication Spotlight: May 2013

Publication spotlight is a series designed to showcase noteworthy BCMB publications from students and faculty. Articles we showcase are newly indexed in PubMed. If you have a recent publication that you are proud of tell us about it.

May

Baile MG, Whited K, Claypool SM. Deacylation on the Matrix Side of the Mitochondrial Inner Membrane Regulates Cardiolipin Remodeling. Mol Biol Cell. 2013 May 1. PMID: 23637464.

Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 in Cells. J Med Chem. 2013 May 1. PMID: 23634668.

April

Stine RR, Matunis EL. Stem cell competition: finding balance in the niche. Trends Cell Biol. 2013 Apr 15. PMID: 23597843.

Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Seop Jeong J, Wu G, Lin J, Gao X, Ni Q, Goel R, Xia S, Ji H, Dalby KN, Birnbaum MJ, Cole PA, Knapp S, Ryazanov AG, Zack DJ, Blackshaw S, Pawson T, Gingras AC, Desiderio S, Pandey A, Turk BE, Zhang J, Zhu H, Qian J. Construction of human activity-based phosphorylation networks. Mol Syst Biol. 2013 Apr 2. PMID: 23549483.

March

Huang Q, Purzycka KJ, Lusvarghi S, Li D, Legrice SF, Boeke JD. Retrotransposon Ty1 RNA contains a 5′-terminal long-range pseudoknot required for efficient reverse transcription. RNA. 2013 Mar. PMID: 23329695.

Shilagardi K, Li S, Luo F, Marikar F, Duan R, Jin P, Kim JH, Murnen K, Chen EH. Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion. Science. 2013 Mar 7. PMID: 23470732.

February

Han L, Ma C, Liu Q, Weng HJ, Cui Y, Tang Z, Kim Y, Nie H, Qu L, Patel KN, Li Z, McNeil B, He S, Guan Y, Xiao B, Lamotte RH, Dong X. A subpopulation of nociceptors specifically linked to itch. Nat Neurosci. 2013 Feb 16. PMID: 23263443.

If you have a publication you would like featured in this month’s Spotlight, please let us know.

Publication Spotlight: April 2013

Publication spotlight is a series designed to showcase noteworthy BCMB publications from students and faculty. Articles we showcase are newly indexed in PubMed. If you have a recent publication that you are proud of, tell us about it.

April

Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M,
Clark HM, Hu S, Hwang W, Seop Jeong J, Wu G, Lin J, Gao X, Ni Q, Goel R, Xia S,
Ji H, Dalby KN, Birnbaum MJ, Cole PA, Knapp S, Ryazanov AG, Zack DJ, Blackshaw S,
Pawson T, Gingras AC, Desiderio S, Pandey A, Turk BE, Zhang J, Zhu H, Qian J.
Construction of human activity-based phosphorylation networks. Mol Syst Biol.
2013 Apr 2. PubMed PMID: 23549483.

March

Shilagardi K, Li S, Luo F, Marikar F, Duan R, Jin P, Kim JH, Murnen K, Chen
EH. Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion. Science. 2013 Mar 7. PubMed PMID: 23470732.

February

Han L, Ma C, Liu Q, Weng HJ, Cui Y, Tang Z, Kim Y, Nie H, Qu L, Patel KN, Li
Z, McNeil B, He S, Guan Y, Xiao B, Lamotte RH, Dong X. A subpopulation of
nociceptors specifically linked to itch. Nat Neurosci. 2013 Feb 16. PubMed PMID: 23263443.

January

Chan W, Schaffer TB, Pomerantz JL. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013 Jan;33(2):429-43. PMID: 23149938.

October (2012)

West-Foyle H, Robinson DN. Cytokinesis mechanics and mechanosensing.
Cytoskeleton (Hoboken). 2012 Oct.  PubMed PMID: 22761196.

If you have a publication you would like featured in this month’s Spotlight, please let us know.

Publication Spotlight: March 2013

Publication spotlight is a series designed to showcase noteworthy BCMB publications from students and faculty. If you have a recent publication that you are proud of, tell us about it.

March

Shilagardi K, Li S, Luo F, Marikar F, Duan R, Jin P, Kim JH, Murnen K, Chen
EH. Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion. Science. 2013 Mar 7. PubMed PMID: 23470732.

January

Chan W, Schaffer TB, Pomerantz JL. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013 Jan;33(2):429-43. PMID: 23149938.

November

Tamura Y, Onguka O, Itoh K, Endo T, Iijima M, Claypool SM, Sesaki H. Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P. J Biol Chem. 2012 Dec 21;287(52):43961-71. PMID: 23124206.

Hobbs RP, Lessard JC, Coulombe PA. Keratin intermediate filament proteins – novel regulators of inflammation and immunity in skin. J Cell Sci. 2012 Nov 15;125(Pt 22):5257-8. PMID: 23377656.

If you have a publication you would like featured in this month’s Spotlight, please let us know.

Publication Spotlight: November 2012

November

Chan W, Schaffer TB, Pomerantz JL. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH Domains that induce Bcl10 ubiquitination
and human lymphoma cell survival. Mol Cell Biol. 2012 Nov 12. PubMed PMID: 23149938.

Stevens EL, Baugher JD, Shirley MD, Frelin LP, Pevsner J. Unexpected Relationships and Inbreeding in HapMap Phase III Populations. PLoS One. 2012;7(11):e49575. doi: 10.1371/journal.pone.0049575. Epub 2012 Nov 19. PubMed PMID: 23185369.

Clayton AM, Cirimotich CM, Dong Y, Dimopoulos G. Caudal is a negative regulator of the Anopheles IMD Pathway that controls resistance to P. falciparum infection. Dev Comp Immunol. 2012 Nov 22. doi:pii: S0145-305X(12)00220-0. 10.1016/j.dci.2012.10.009. [Epub ahead of print] PubMed PMID: 23178401.

October

Zhu H, Cox E, Qian J. Functional protein microarray as molecular decathlete: A
versatile player in clinical proteomics. Proteomics Clin Appl. 2012 Oct 2. doi:
10.1002/prca.201200041. PubMed PMID: 23027439.

August

Hatori Y, Clasen S, Hasan NM, Barry AN, Lutsenko S. Functional partnership of
the copper export machinery and glutathione balance in human cells. J Biol Chem.
2012 Aug 3;287(32):26678-87. doi: 10.1074/jbc.M112.381178. Epub 2012 May 30.
PubMed PMID: 22648419.

If you have publication you would like featured in this month’s Spotlight, please let us know.

Publication Spotlight: October 2012

Publication spotlight is a series designed to showcase noteworthy BCMB publications from students and faculty. If you have a recent publication that you are proud of, tell us about it.

-Matt Shirley

October

Liu Q, Sikand P, Ma C, Tang Z, Han L, Li Z, Sun S, Lamotte RH, Dong X. Mechanisms of Itch Evoked by β-Alanine. J Neurosci. 2012 Oct 17;32(42):14532-7. doi: 10.1523/JNEUROSCI.3509-12.2012. PubMed PMID: 23077038.

Whited K, Baile MG, Currier P, Claypool SM. Seven Functional Classes of Barth
Syndrome Mutation. Hum Mol Genet. 2012 Oct 24. [Epub ahead of print] PubMed PMID:

Cho, J.Y., Chak, K., Andreone, B.J., Wooley, J.R., and Kolodkin, A.L. (2012).  The extracellular matrix proteoglycan perlican facilitates transmembrane semaphorin-mediated repulsive guidance. Genes and Development 26, 2222-2235 [PMCID (in progress): PMC23028146].

July

Matunis EL, Stine RR, de Cuevas M. Recent advances in Drosophila male germline
stem cell biology. Spermatogenesis. 2012 Jul 1;2(3):137-144. PubMed PMID:
23087833; PubMed Central PMCID: PMC3469437
.
Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus
OB, Tomaselli G, Nan F, Laugwitz KL, Li M. Modulation of hERG potassium channel
gating normalizes action potential duration prolonged by dysfunctional KCNQ1
potassium channel. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11866-71. doi:
10.1073/pnas.1205266109. Epub 2012 Jun 28. PubMed PMID: 22745159

June

Zhong J, Kim MS, Chaerkady R, Wu X, Huang TC, Getnet D, Mitchell CJ, Palapetta
SM, Sharma J, O’Meally RN, Cole RN, Yoda A, Moritz A, Loriaux MM, Rush J,
Weinstock DM, Tyner JW, Pandey A. TSLP signaling network revealed by SILAC-based
phosphoproteomics. Mol Cell Proteomics. 2012 Jun;11(6):M112.017764. doi:
10.1074/mcp.M112.017764. Epub 2012 Feb 16. PubMed PMID: 22345495
Congratulations, everyone!

Publication Spotlight: September 2012

Publication spotlight is a series designed to showcase noteworthy BCMB publications from students and faculty. If you have a recent publication that you are proud of, tell us about it.

-Matt Shirley

September

Phua SC, Pohlmeyer C, Inoue T. Rapidly Relocating Molecules Between Organelles
to Manipulate Small GTPase Activity. ACS Chem Biol. 2012 Sep 25. [Epub ahead of
print] PubMed PMID: 22999378.

Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P,
Werb Z, Ewald AJ. ECM microenvironment regulates collective migration and local
dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S
A. 2012 Aug 23. [Epub ahead of print] PubMed PMID: 22923691.

Dancy BM, Crump NT, Peterson DJ, Mukherjee C, Bowers EM, Ahn YH, Yoshida M, Zhang J, Mahadevan LC, Meyers DJ, Boeke JD, Cole PA.  Live-Cell Studies of p300/CBP Histone Acetyltransferase Activity and Inhibition.  Chembiochem. 2012 Sep 24;13(14):2113-21. doi: 10.1002/cbic.201200381. Epub 2012 Sep 7.  PMID: 22961914

October

Duan R, Jin P, Luo F, Zhang G, Anderson N, Chen EH. Group I PAKs function
downstream of Rac to promote podosome invasion during myoblast fusion in vivo. J
Cell Biol. 2012 Oct 1;199(1):169-85. doi: 10.1083/jcb.201204065. Epub 2012 Sep
24. PubMed PMID: 23007650.

Herb BR, Wolschin F, Hansen KD, Aryee MJ, Langmead B, Irizarry R, Amdam GV,
Feinberg AP. Reversible switching between epigenetic states in honeybee
behavioral subcastes. Nat Neurosci. 2012 Oct;15(10):1371-3. doi: 10.1038/nn.3218.
Epub 2012 Sep 16. PubMed PMID: 22983211.

Congratulations!